Our Therapeutic Areas

The cornerstone of our research into new medicines is focused on those disease areas where we have built significant expertise over time. We are concentrating our research efforts and investment in these key therapeutic areas: CardioMetabolic diseases; Central Nervous System diseases; Immunology and Respiratory diseases; and Oncology and Cancer Immunology.


Immunology and Respiratory Research

Our Immunology and Respiratory discovery research therapeutic area combines our long-standing leadership in respiratory diseases with the proven ability to address unmet needs in immune-mediated diseases. Our teams are focused on the discovery and development of new therapeutic concepts that will radically alter the progression of chronic inflammatory and autoimmune diseases.

Our experience

Our scientific expertise includes mechanisms and targets that underpin chronic obstructive pulmonary disease (COPD), inflammatory bowel disease (IBD), pulmonary fibrosis, systemic sclerosis, systemic lupus erythematosus and asthma.

Scientists in our dedicated immunology and respiratory research and development centers, located in the USA and Germany, are working, together with our academic and industry partners, to offer patients and doctors new therapeutic options to treat these chronic and often debilitating disorders.

 

Our research focus

We focus on core scientific themes to arrest the natural history of chronic inflammatory and autoimmune diseases:

  • Mucosal barrier injury and repair
  • Aberrant tissue remodelling
  • Novel approaches to regulate innate and adaptive immune responses.