Our Immunology research and partnering focus

Our immunology research and development program is anchored firmly by a panel of external collaborations to deliver promising new compounds with the potential to transform the treatment of immune-mediated diseases.

We are seeking collaboration and in-licensing opportunities from early research stage through late pre-clinical development in the following areas:

• Crohn’s disease: including specific approaches for fistulizing and refractory ileal Crohn’s disease
• Ulcerative colitis
• Inflammatory skin diseases: including systemic sclerosis-scleroderma.

Within these areas, our specific research interests offer further opportunities for collaboration:

• Human genetics: identification of new therapeutic concepts and biomarkers
• Gut & skin epithelial barrier dysfunction: regulation of injury, inflammation and repair, including host-microbiome interactions
• Control of aberrant tissue remodeling and fibrosis
• Innate immune signaling pathways
• Immune regulatory receptors.